I ended up creating a listserv email where I have my subscriptions sent. But, often, I find I have a subscription to something I don't need or want, or that I have subscribed to a web 2.0 tool to experiment and realize it isn't for me.
I came across a link in my twitter feed the other day that caught my eye-- Just delete me. It is a directory of links to delete your subscriptions. I looked it over and there is a ton of options there to help unsubscribe from the mass number of lists and websites. The page offers information about difficulty of unsubscribing as well, which might benefit you because, if you are like me, spending 20 minutes to delete a subscription isn't worth it. I will just delete the email, it's faster.
I am going to start looking through it and deleting things I know I never use. I am sure if you look at it, something will strike your fancy as well.